Cameron and Jo

This article focuses on the interactions between Cameron and Jo.

Overview
Jo thinks of herself as the strongest contestant and thinks of everyone else, especially the weaker-looking Cameron, as weaklings. Throughout the season, Jo picks on Cameron, and thinks of him as the most expendable member of their team due to his weak body structure. Cameron, on the other hand, doesn't like Jo's treatment of him, but learns much from her. However, as the season progresses, Cameron learns how to stand up for himself and eventually, leads Jo to her own downfall in Up, Up And Away In My Pitiful Balloon. Although Jo was angry of Cameron's betrayal, the two of them parted on friendly terms, but the conflict has yet to end, as Jo did not support Cameron in the finale.

Opening sequence
Cameron is caught by Jo after being sent flying in the air, but Jo drops him to race Brick.

Bigger! Badder! Brutal-er!
Jo swims past Cameron and refuses to help him despite that he was drowning.

Truth or Laser Shark
While the contestants are walking towards the lake for the next challenge, Cameron says he hopes the challenge isn't too physical, causing Jo to reply by saying he would since he couldn't possibly handle anything physical and that it's impossible to win Total Drama without getting physical. After the first challenge, Cameron is fed up with Jo at tells her that he has as much right to be on this show as she does and that he'll prove it in the next challenge.

Ice Ice Baby
Jo seemed a little bit annoyed to see Cameron nervously guarding their team's flag.

Finders Creepers
Jo refers to Cameron as the team's most expendable player and throws him into a hole in a tree. When Anne Maria and Mike go missing and Cameron wants to try to find them, Jo prefers to continue with the challenge, upsetting Cameron that she has little concern for her teammates.

Backstabbers Ahoy!
When Anne Maria objected to Jo being the diver, Jo shoved the dive helmet onto Cameron's head, its weight causing him to tip over. This action made Cameron support Jo in the challenge out of intimidation. During the water-skiing challenge, when Jo's seagull gun was jammed, she tells Cameron to "take one for the team." She then threw him to the bell they needed to ring to win the challenge, but he crashes into Lightning, who was also flying across the air. This severely injured Cameron.

Runaway Model
Cameron, along with the rest of the Maggots (including Brick, who's now on Rats), looks frightened by Jo's new look.

Grand Chef Auto
After Chris announced the merge, Cameron went over to Jo to see if she wanted to form an alliance which Jo declined. When Cameron is spray painting his graffiti, Jo laughs at him, telling him that it isn't art school.

Up, Up And Away In My Pitiful Balloon
The conflict between the two of them reaches a breaking point in this episode. Jo forces Cameron to form an alliance with her earlier in the episode. Jo forces Cameron to make her flying machine to be the best so she can get first place and focus less on his own. Despite Cameron winning the first part of the challenge, Jo takes his prize, a smoke machine ,and Cameron allows it. While chasing Heather, Jo commands Cameron to shield her from the statues Heather are throwing, injuring him in the process. Eventually, after being persuaded by Lightning, Cameron betrays Jo by activating the self destruct sequence on the smoke machine that he place. At the campfire ceremony, Cameron votes for Jo along with Lightning and she is eliminated. This prompts Jo to call him a traitor.

Brain vs. Brawn: The Ultimate Showdown
Despite leaving on a seemingly-positive note with Cameron and a negative note with Lightning, Jo was the only member of the whole cast who rooted for Lightning to win instead of Cameron. She cheered for Lightning as he attacked Cameron and was noticeably upset when Cameron was declared the winner. In the alternate ending, Jo complains that she should have won the million since she lead both Cameron and Lightning to the finale.

Bigger! Badder! Brutal-er!
Cameron supports Jo in the challenge by attempting to calculate where exactly on the trampoline Jo should jump in order to grab the axe.

Ice Ice Baby
Cameron accepts Jo being the team captain and follows her orders and the two seem to cooperate well in the challenge. The two of them work well together in making Mike transform into his Svetlana personality, with Cameron making a grand introduction and Jo allowing him to fly outside their fort, leading to him ultimately capturing the flag for the win.

Finders Creepers
Cameron looks for Jo after he finds Anne Maria and Mike and is worried when he is unable to find her. Jo is impressed that Cameron lasted quite long in the challenge after he's taken by the giant spider, and Cameron, in the confessional, states it was the nicest thing Jo ever said to him.

Backstabbers Ahoy!
After Cameron won the challenge for the team, Jo appreciated him doing so and complimented him.

Runaway Model
When Cameron came up with an idea to win the challenge, Jo respected it and went along with it.

A Mine Is a Terrible Thing to Waste
When Cameron was faced with the dilemma of waking up an unconscious Mike after a mine cart crash, he asked himself "What would Jo do?" He then proceeded to yell at Mike and hit him on the head with a flashlight, waking him up. This subtly implies that, despite their conflict, Cameron has gained respect for Jo as a leader.

Grand Chef Auto
Cameron asks Jo for an alliance. They both look at Lightning strangely.

Up, Up And Away In My Pitiful Balloon
When Cameron betrays Jo at the end of the episode and has her eliminated, he tells her that he did so because "he learned from the best" (meaning her). Surprisingly, Jo is proud of this and tells Cameron "Good technique, kid," showing he has finally earned her respect.

Brain vs. Brawn: The Ultimate Showdown
Despite rooting for Lightning and being visibly upset when Cameron won, Jo was excited to hear that Cameron would split the prize money with everyone else. She declared that she would use her share to open up her own dream gym.

Trivia

 * Both have been mistaken for the opposite gender by Lightning:
 * In Bigger! Badder! Brutal-er!, Cameron was called a "little girl" after Lightning had saved him from drowning.
 * Jo is referred to as a "male" by Lightning throughout season four until at the end of Up, Up And Away In My Pitiful Balloon.
 * Both are the first (and currently the only) two members of the new cast to share a confessional.